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Effects of TA-65, Imetelstat and TGF-β1 on catalase in vitro. MEF cells were pre-treated with TA-65 (2 µM) and/or Imetelstat (1 µM) during 24 h, followed by TGF-β treatment (10 ng/mL) for 48 h. Catalase expression was evaluated by immunostaining (a). Representative images are available in Supplementary Fig. S4. Catalase activity of cell lysates was quantified using an Amplex Red Catalase Assay kit (b). n = 4 samples per group. Data are presented as mean ± SEM. *p < 0.05.
