TABLE 1.
Subject demographics, GluCEST DAI and volumetric DAI for patient cohort
| Patient ID | Age | Seizure duration | Seizure localization | MRI brain | PET | Surgery | Pathology | Outcome | Group | GluCEST modality | Hippocampal GluCEST DAI | Hippocampal volume DAI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P007 | 55F | 5 years | Right | R MTS | R temporal hypometabolism | R temporal lobectomy | MTS | Engel IA | MTLe‐L | 2D | −0.0349 | −0.2770 |
| P010 | 61F | 40 years | Left | L MTS | L temporal hypometabolism | L temporal laser ablation | NA | Engel IA | MTLe‐L | 2D | −0.1263 | −0.2711 |
| P012 | 59F | 6 years | Right | R MTS | Unremarkable | R temporal laser ablation | NA | Engel IA | MTLe‐L | 2D | −0.0076 | −0.0274 |
| P015 | 47F | 20 years | Left | L MTS | L anterior and mesial temporal hypometabolism | L temporal lobectomy | MTS | Engel IA | MTLe‐L | 2D | −0.0441 | −0.3347 |
| P019 | 56F | 8 years | Suspected left | Probable L MTS | Left temporal hypometabolism | No surgery | NA | NA | MTLe‐L | 3D | −0.0976 | −0.2434 |
| P021 | 38 M | 12 years | Right | Non‐lesional | R anterior hypometabolism | R partial temporal lobectomy | MTS | Engel IA | MTLe‐L | 3D | −0.1949 | 0.1166 |
| P025 | 36 M | 31 years | Right | Non‐lesional | R temporal hypometabolism | R amygdalo‐hippocampectomy | MTS | Engel IA | MTLe‐L | 3D | −0.0473 | −0.3878 |
| P029 | 40F | 16 years | Left | Non‐lesional | Left anterior temporal hypometabolism | L temporoamygdalo hippocampectomy | Mild hippocampal sclerosis | Engel IB | MTLe‐L | 3D | −0.0347 | −0.0010 |
| P046 | 31F | 15 years | Left | Probable L MTS | L anterolateral temporal hypometabolism | 2 L temporal laser ablation | NA | Engel IA | MTLe‐L | 2D | −0.0676 | −0.1094 |
| P064 | 56 M | 3 years | Left | L MTS | Bilateral temporal hypometabolism | L temporal laser ablation | NA | Engel IIIA | MTLe‐L | 2D | 0.0284 | −0.1538 |
| P023 | 40 M | 5 years | Left | Non‐lesional | Left medial temporal hypometabolism | NA | NA | NA | MTLe‐NL | 3D | 0.0480 | 0.0070 |
| P026 | 32F | 4 years | Left | Non‐lesional | Unremarkable | NA | NA | NA | MTLe‐NL | 3D | 0.0357 | −0.0070 |
| P051 | 25 M | 6 years | Right | Non‐lesional | Right mesial temporal hypometabolism | R Temporal laser ablation | NA | Engel IA | MTLe‐NL | 2D | 0.0915 | −0.0110 |
| P070 | 29 M | 10 years | Left | Non‐lesional | Left temporal hypometabolism | 2 L Temporal laser ablations | NA | Engel IIIA | MTLe‐NL | 2D | 0.0125 | −0.0450 |
Abbreviations: MTLe‐NL, non‐lesional mesial temporal lobe epilepsy; MTLe‐L, lesional mesial temporal lobe epilepsy; MTS, mesial temporal sclerosis.