FIGURE 3.

Immunohistochemical analysis of BCAM, LAMA5 and COL1 in matched samples of OC metastases and spheroids from ascites. Paraffin sections from metastases at different stages (early metastases: tumour cells still near the surface; advanced metastases: deeply invading larger tumour masses) and spheroids from ascites were stained by immunohistochemistry as described in Materials and Methods. A quantification of the images is shown in Table 2 (patient OC114). Further examples are depicted in Figure S13 and quantified in Table 2. Scale bar: 50 μm