Skip to main content
. 2023 Jan 16;13(1):e1176. doi: 10.1002/ctm2.1176

TABLE 1.

Functional annotation of genes associated with a poor overall survival (OS) of human adenocarcinomas. Genes with a z‐score > 2 (i.e., p < .05 and hazard ratio > 1) were retrieved from the PRECOD dataset and analysed for enrichment of GO biological processes. The table lists the top term for each instance, including the number of enriched genes, the fold enrichment and the FDR. Only terms with a fold enrichment ≥ 2.5 and an FDR < 0.01 were included. The data for OC are highlighted in red.

Entity GO biological process n Fold FDR
Bladder Mitotic cell cycle 128 3.52 1.2E−26
Breast Mitotic cell cycle 231 2.50 7.5E−22
Colon Vasculature development 67 2.64 1.1E−08
Liver Regulation of intrinsic apoptotic signalling pathway 23 3.59 5.5E−04
Lung Mitotic cell cycle 206 2.64 2.8E−26
Ovarian ECM organisation 77 2.80 2.2E−10
Pancreatic Cellular response to DNA damage stimulus 76 2.59 8.1E−10
Prostate Mitotic cell cycle 67 4.40 4.2E−14