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. 2023 Jan 12;11(1):e006136. doi: 10.1136/jitc-2022-006136

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Pan-Immune-Inflammation Value (PIV) at screening was significantly lower in mCRC participants who received clinical benefit (PR+SD) compared with those who did not receive benefit (PD+NE). PIV=Neutrophils×Platelets×Monocytes/Lymphocytes. Median values are indicated by horizontal lines. Data failed Shapiro-Wilk normality test so comparison was performed with Mann-Whitney test (*p<0.05). mCRC, metastatic colorectal cancer; PR, partial response; SD, stable disease; NE, not evaluable.