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. 2022 Nov 22;9(2):e002147. doi: 10.1136/openhrt-2022-002147

Table 4.

Top 10 national priorities for research in adult congenital heart disease (CHD)

Rank Priority for research
1 How can less invasive interventions be performed for CHD with the same outcomes as open-heart surgery?
2 How can the longevity of the Fontan circulation be prolonged and the impact of complications (eg, liver, protein-losing enteropathy, renal, endocrine, fertility) be reduced?
3 What is the impact of living with CHD on mental health in adults and how can this be improved through access to psychological support and other therapies?
4 How can technology be used to deliver personalised care and improve outcomes of those with CHD (eg, artificial intelligence, 3D printing, genomics, stem cells, organ regeneration)?
5 What are the risks and limitations associated with pregnancy, childbirth and motherhood for women with CHD, and what information and support is available?
6 What are the best treatment strategies for heart failure in adults with CHD, in particular those with a systemic right ventricle?
7 How can the management of arrhythmias, including sudden cardiac death, in adults with CHD be improved?
8 How can the indications, timing of referral and outcomes of transplantation and long-term mechanical support in adults with CHD be improved?
9 What is the impact of living with CHD on quality of life in adults and how can this be improved?
10 How can the frequency or need for reoperations be reduced for people with CHD (eg, improved valve/conduit longevity or that grow with the patient)?