Table 3. Serum levels of TNF-α and IL-1β before and after splenectomy (n=12; mean ± SD).
| Group | Control | Sham | Splenectomy | Mdivi-1 | DMSO |
|---|---|---|---|---|---|
| Preoperatively | |||||
| TNF-α (ng/L) | 10.38±3.2 | 11.3±3.05 | 9.8±2.47 | 9.02±2.88 | 11.03±4.38 |
| IL-1β (ng/L) | 7.36±2.69 | 7.89±2.82 | 6.73±1.75 | 7.57±2.69 | 6.98±2.06 |
| 3 days postoperatively | |||||
| TNF-α (ng/L) | 9.18±2.8 | 10.42±1.81 | 15.35±4.56 | 12.76±3.44 | 14.66±1.73 |
| IL-1β (ng/L) | 7.87±2.01 | 8.37±3.32 | 11.77±4.14 | 9.27±1.61 | 10.67±1.73 |
| 7 days postoperatively | |||||
| TNF-α (ng/L) | 10.15±2.6 | 10.63±3.11 | 14.04±3.33 | 11.04±1.68 | 13.53±1.97 |
| IL-1β (ng/L) | 7.22±2.67 | 7.53±1.78 | 10.14±2.22 | 8.1±2.04 | 10.21±2.35 |
TNF-α, tumor necrosis factor α; IL-1β, interleukin-1β; DMSO, dimethyl sulfoxide.