Table 1.
Univariate analysis comparing characteristics between patients with and without REND
| Characteristics | With REND (n = 13) | Without REND (n = 22) | p value |
|---|---|---|---|
| Age, years | 75 (65–858) | 63.5 (54–75.8) | 0.054 |
| Male | 8 (57.1) | 16 (76.2) | 0.28 |
| Hypertension | 11 (84.6) | 20 (90.9) | 0.62 |
| Dyslipidemia | 5 (38.5) | 11 (61.5) | 0.73 |
| Diabetes mellitus | 8 (61.5) | 3 (13.6) | 0.007 |
| Smoking | 9 (69.2) | 16 (76.2) | 0.70 |
| Heart disease as embolic source | 1 (11.1) | 5 (35.7) | 0.34 |
| Subtype classification | 0.15 | ||
| LAD | 8 (61.5) | 13 (59.1) | |
| CES | 3 (23.1) | 1 (4.5) | |
| Others | 2 (15.4) | 3 (13.6) | |
| TIA | 0 (0) | 5 (22.7) | |
| Initial NIHSS score | 4 (3–5) | 1 (0–2.8) | <0.001 |
| Onset-to-door time, min | 169 (80–420) | 340 (157.5–627.5) | 0.23 |
| Patent ICT and MCA | 8 (61.5) | 14 (63.6) | 1.00 |
| Systolic blood pressure on arrival, mm Hg | 155 (150–181) | 135 (130–170) | 0.16 |
| Diastolic blood pressure on arrival, mm Hg | 86 (78–101) | 75 (66–109) | 0.17 |
| IVT | 4 (30.9) | 0 (0) | 0.014 |
| MT | 3 (23.1) | 0 (0) | 0.044 |
| Bypass surgery | 2 (15.4) | 0 (0) | 0.13 |
| sICH | 0 (0) | 0 (0) | 1.00 |
| mRS at discharge | 5 (4–5) | 0 (0–1) | <0.001 |
Data are presented as number (%) or median (IQR). REND, recurrence of stroke or early neurological deterioration with increment in NIHSS score ≥1 during hospital stay; IQR, interquartile range; TOAST, Trial of ORG 10172 in Acute Stroke Treatment; LAD, large artery disease; CES, cardioembolic stroke; TIA, transient ischemic attack; NIHSS, National Institutes of Health Stroke Scale; ICT, internal carotid artery terminus; MCA, middle cerebral artery; IVT, intravenous thrombolysis; MT, mechanical thrombectomy; sICH, symptomatic intracranial hemorrhage; mRS, modified Rankin Scale.