Skip to main content
. 2022 Dec 31;27(4):423–435. doi: 10.3746/pnf.2022.27.4.423

Fig. 7.

Fig. 7

Effects of Naticol on skin melanogenesis-related factors, tyrosinase activity (A), nitric oxide (B), cAMP (C), protein band (D), p-PKA (E), p-CREB (F), MITF (G), TRP-1 (H), and TRP-2 (I) in the dorsal skin of SKH-I hairless mice exposed to UVB. NC, AIN93G; C, UVB irradiation+AIN93G; PC1, UVB irradiation+AIN93G with L-ascorbic acid (100 mg/kg); PC2, UVB irradiation+AIN93G with arbutin (100 mg/kg); Naticol150, UVB irradiation+AIN93G with Naticol collagen (150 mg/kg); Naticol300, UVB irradiation+AIN93G with Naticol collagen (300 mg/kg). Values are presented as mean±SD. Different letters (a-f) represent significant differences at P<0.05, as determined by Duncan’s multiple range test. Biomarkers used for Western blot analysis are listed in Table 1. NC, normal control; C, control; PC, positive control; UVB, ultraviolet B.