Figure 5. Multiple sequence alignment of the CIC::DUX4 fusion transcripts type 1 and type 2 with previously reported CIC::DUX4 fusion transcripts by Cocchi et al. (38), Gambarotti et al. (34), Kao et al. (60), Machado et al. (32), Tsukamoto et al. (37), Yoshida et al. (41) and Italiano et al. (6). CIC sequence is written in red and DUX4 sequence in black letters. The tetranucleotide AGGT which was found at the junction and was common to both CIC and DUX4 is written in blue letters. The stop codon TAG or TGA is underlined.