Skip to main content
Journal of Experimental & Clinical Cancer Research : CR logoLink to Journal of Experimental & Clinical Cancer Research : CR
. 2023 Jan 17;42:24. doi: 10.1186/s13046-023-02599-z

Retraction Note: IMP3 accelerates the progression of prostate cancer through inhibiting PTEN expression in a SMURF1-dependent way

Xiang Zhang 1,2,#, Dawei Wang 1,2,#, Boke Liu 1,2,#, Xingwei Jin 1,2, Xianjin Wang 1,2, Junwei Pan 1,2, Weichao Tu 1,2, Yuan Shao 1,2,
PMCID: PMC9843829  PMID: 36650556

Retraction Note: J Exp Clin Cancer Res 39, 190 (2020)

https://doi.org/10.1186/s13046-020-01657-0

The Editor in Chief and all authors have retracted this article. After publication, concerns were raised about the following issues with the images:

  • Fig. 1C: the tumour-IHC:IMP3 panel appears very similar to the tumour-SAT1 panel in Fig 2N in a paper by different authors that was under submission at the same time [1].

  • Fig. 2B: the LNCap IMP3 blot appears very similar to the SK-KEP-1 ACSL4 blot in Fig 2B in a previously-published paper by different authors [2].

  • Fig. 2F contains multiple panels that seem to overlap with panels in Fig 1C a previously-published paper by different authors [3], Fig 1D in a previously-published paper by different authors [4], as well as Fig 5E, 6E and 7H in a paper by different authors that was under submission at the same time [1].

  • Fig. 4A: the SMURF1 blot appears very similar to the N-Cahedrin blot in a paper by different authors that was under submission at the same time [5].

  • Fig. 6F contains two tumours that appear similar to those in Figs 2M and 7H in in a previously-published paper by different authors [6].

The authors supplied the raw data, but in view of the multiple nature of the overlaps, the Editor in Chief has lost confidence in the integrity of the results of the article. All authors agree with this retraction.

Footnotes

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Xiang Zhang and Dawei Wang contributed equally to this work as co-first authors. Boke Liu contributed as the third author

References

  • 1.Xiao Y, Li C, Wang H, Liu Y. LINC00265 targets miR-382-5p to regulate SAT1, VAV3 and angiogenesis in osteosarcoma. Aging. 2020;12(20):20212–20225. doi: 10.18632/aging.103762. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Wang J, Wang Z, Yuan J, Wang J, Shen X. The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma. Aging. 2020;12(9):1945–4589. doi: 10.18632/aging.103092. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Sun L, Jiang C, Xu C, Xue H, Zhou H, Gu L, Liu Y, Xu Q. Down-regulation of long non-coding RNA RP11-708H21.4 is associated with poor prognosis for colorectal cancer and promotes tumorigenesis through regulating AKT/mTOR pathway. Oncotarget **. 2017;8:27929–27942. doi: 10.18632/oncotarget.15846. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4.Hu XM, Xiang JJ, Xiao BL, Huang YF, Xie JP. Wogonoside promotes apoptosis in gastric cancer AGS and SGC-7901 cells through induction of mitochondrial dysfunction and endoplasmic reticulum stress. FEBS Open Bio. 2019;9(8):1469–1476. doi: 10.1002/2211-5463.12693. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
  • 5.Ghosh Choudhury G, Chen Y, Zhang W, Shen L, Kadier A, Huang J, et al. Downregulation of Long Noncoding RNA LUCAT1 Suppresses the Migration and Invasion of Bladder Cancer by Targeting miR-181c-5p. Biomed Res Int. 2020:2314–6133. 10.1155/2020/4817608. [DOI] [PMC free article] [PubMed]
  • 6.Yang J, Yu L, Yan J, Xiao Y, Li W, Xiao J, Yu X. Circular RNA DGKB promotes the progression of neuroblastoma by targeting miR-873/GLI1 Axis. Front Oncol. 2020;10:1104. doi: 10.3389/fonc.2020.01104. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Experimental & Clinical Cancer Research : CR are provided here courtesy of BMC

RESOURCES