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. 2023 Jan 17;24:10. doi: 10.1186/s13059-023-02847-7

Table 2.

Model performance for ROH prediction. Here, we test ROH-HMM in four different cases of simulations: control (without ROH, ascertainment bias or contamination), R (with ROH), RA (with ROH and ascertainment bias), RC (with ROH and contamination)

Coverage Control (Sp) R (Se) R (Sp) RA (Se) RA (Sp) RC (Se) RC (Sp)
4x > 0.99 0.97 0.98 0.97 0.98 0.97 0.97
0.5x > 0.99 0.96 0.98 0.96 0.98 0.96 0.97
0.2x > 0.99 0.92 0.98 0.91 0.98 0.93 0.97
0.1x > 0.99 0.85 0.98 0.83 0.97 0.82 0.97
0.05x 0.99 0.65 0.96 0.55 0.96 0.57 0.96