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. 2023 Jan 17;21:31. doi: 10.1186/s12967-023-03877-2

Fig. 5.

Fig. 5

NOC2L, Aurora B and P53 Form a Complex. NOC2L binds to P53, and recruits Aurora B to phosphorylate P53 on Ser183, Ser269 and Thr284 sites. After phosphorylation, P53 activity is inhibited