Table 1.
The effects of GSB-214 in the scopolamine-induced model of amnesia in the novel object recognition test
| Group | Number of animals per group |
Discrimination index | |
|---|---|---|---|
| Test 1 (1 h) | Test 2 (24 h) | ||
| Control | 9 | 0.57 ± 0.05 | 0.53 ± 0.06 |
| SC | 10 | 0.3 ± 0.06* | 0.23 ± 0.06** |
| SC+GSB-214 (0.05 mg/kg) |
10 | 0.48 ± 0.07 | 0.48 ± 0.04# |
| SC+GSB-214 (0.1 mg/kg) |
9 | 0.45 ± 0.07 | 0.47 ± 0.05# |
| SC+GSB-214 (1.0 mg/kg) |
10 | 0.33 ± 0.06 | 0.44 ± 0.08 |
The data are presented as the mean ± standard error of the mean. **p < 0.01, *p < 0.05 compared to the Control group; #p < 0.05 compared to the SC group (one-way ANOVA, the Dunnett’s test).