Table 3.
The Trk receptor inhibitor completely eliminates the mnemotropic effect of GSB-214 on long-term memory
| Group |
Number of animals per group |
Discrimination index | |
|---|---|---|---|
| Test 1 (1 h) | Test 2 (24 h) | ||
| Control | 12 | 0.53 ± 0.07 | 0.47 ± 0.06 |
| GSB-214 (0.1 mg/kg) |
13 | 0.5 ± 0.05 | 0.73 ± 0.03*** |
| GSB-214 (0.1 mg/kg)+ K252A |
12 | 0.53 ± 0.06 | 0.36 ± 0.03#### |
| K252A | 13 | 0.54 ± 0.06 | 0.43 ± 0.05 |
The data are presented as the mean ± standard error of the mean. ***p < 0.001 compared to the Control group; ####p < 0.0001 compared to the GSB-214 group (twoway ANOVA, the Tukey’s test).