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. Author manuscript; available in PMC: 2023 Jan 17.
Published in final edited form as: Mol Pharm. 2020 Sep 2;17(10):3900–3914. doi: 10.1021/acs.molpharmaceut.0c00641

Figure 7.

Figure 7.

Effect of dual injections of 0.5× μNETs and 0.5× nNETs one week apart. Cytokine measurements were made using samples collected 2 h after the second injection. Concentration measurements (represented as symbols) for (a–c) IL-6, (d–f) IL-10, (g–i) TNF-α, and (j–l) MCP-1 in the blood serum, liver, and spleen, respectively, are presented. Horizontal bars represent the mean values associated with a given cytokine concentration. Bracket with *** asterisks above it indicates statistically significant differences between the shown pairs (p < 0.001). None of the other t-tests resulted in statistically significant p-values. Therefore, statistical significances of p < 0.05 and p < 0.01 are not indicated.