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. Author manuscript; available in PMC: 2023 Jan 17.
Published in final edited form as: N Engl J Med. 2022 Apr 11;386(21):1973–1985. doi: 10.1056/NEJMoa2202170

Figure 2 (facing page). Pathological Complete Response According to Blinded Independent Pathological Review.

Figure 2 (facing page).

Panel A shows pathological complete response in the primary analysis population, and Panel B shows pathological complete response in prespecified patient subgroups. Pathological complete response was defined as 0% residual viable tumor cells in both primary tumor (lung) and sampled lymph nodes. According to the intention-to-treat principle, patients who did not undergo surgery were counted as not having had a response for the primary analysis. In Panel A, the between-group difference was calculated by means of a stratified Cochran–Mantel–Haenszel method.