TABLE 2.

Univariate and multivariate analyses of overall survival in primary gastric T‐NHL patients (N = 164)

Variable	Univariate analysis	P value	Multivariate analysis I	P value	Multivariate analysis II	P value
	HR (95% CI)		HR (95% CI)		HR (95% CI)
Age at diagnosis (years old)		0.001		0.009		0.026
≤ 60	Reference		Reference		Reference
61 ~ 75	1.695 (1.114 ~ 2.578)	0.014	1.664 (1.093 ~ 2.532)	0.018	1.910 (1.138 ~ 3.203)	0.014
> 75	2.272 (1.458 ~ 3.539)	< 0.001	1.975 (1.251 ~ 3.116)	0.003	1.888 (1.016 ~ 3.509)	0.044
Sex (Male vs. Female)	0.944 (0.652 ~ 1.366)	0.759
Race (White vs. Black/Other)	1.227 (0.854 ~ 1.761)	0.269
Histology type		0.940
ALCL‐ALK+	Reference
PTCL‐NOS	1.024 (0.703 ~ 1.491)	0.903
Other T‐NHL	1.155 (0.517 ~ 2.578)	0.725
Primary site		0.463
Upper third of stomach	Reference
Mid and low of stomach	1.551 (0.890 ~ 2.704)	0.121
Overlapping lesion of stomach	1.351 (0.669 ~ 2.727)	0.401
Stomach, NOS	1.457 (0.857 ~ 2.477)	0.165
Ann Arbor stage (I/II vs. III/IV)	1.051 (0.872 ~ 1.268)	0.600
Symptom (A vs. B)	1.193 (0.736 ~ 1.935)	0.474
Chemotherapy (No/unknown vs. Yes)	0.559 (0.394 ~ 0.793)	0.001	0.653 (0.453 ~ 0.939)	0.022
Radiotherapy (No/unknown vs. Yes)	0.371 (0.187 ~ 0.735)	0.004	0.411 (0.207 ~ 0.816)	0.011
Surgery (No/unknown vs. Yes)	0.851 (0.521 ~ 1.388)	0.581
Treatment modality		0.064				0.069
Chemotherapy only	Reference				Reference
Surgery/Radiotherapy only	0.664 (0.306 ~ 1.442)	0.301			0.736 (0.333 ~ 1.628)	0.450
Chemotherapy plus Surgery	0.856 (0.456 ~ 1.609)	0.629			0.841 (0.440 ~ 1.606)	0.600
Chemotherapy plus Radiotherapy	0.311 (0.130 ~ 0.743)	0.009			0.306 (0.127 ~ 0.739)	0.008

Abbreviations: ALCL, anaplastic large cell lymphoma; PTCL, peripheral T‐cell lymphoma.