TABLE 4.
Meta‐analysis results of tumor markers and related factors
| Outcomes | Trials | SM | SMD, 95% CI | I 2 (%) | p | PB |
|---|---|---|---|---|---|---|
| CEA | 12 | REM | −1.83 (−2.69, −0.96) | 96 | <0.0001 | Yes |
| CA199 | 7 | REM | −0.86 (−1.32, −0.40) | 81 | 0.0003 | Unclear |
| CA125 | 4 | REM | −1.73 (−3.14, −0.32) | 96 | 0.0162 | Unclear |
| CA724 | 2 | REM | −2.39 (−7.14, 2.36) | 99 | 0.3246 | Unclear |
| TNF‐α | 2 | REM | 0.13 (−2.65, 2.91) | 98 | 0.9262 | Unclear |
Note: Forest of all results are in Figure S3.
Abbreviations: CI, confidence interval; FEM, fixed‐effects model; PB, Publication bias; REM, random‐effects model; SM, statistical method; SMD, standardized mean difference.