TABLE 4.
Multivariable logistic regression analyses of the association between ADH1B and ALDH2 polymorphisms in cancer of pancreatic
| Variable | Model 1 | p value | Model 2 | p value | Model 3 | p value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | 95% CI | 95% CI | |||||||
| Age (ref = <40) | ||||||||||||
| 41–60 | 1.87 | 1.00 | 3.49 | 0.33 | 1.86 | 0.99 | 3.48 | 0.33 | 1.86 | 1.00 | 3.48 | 0.33 |
| 61–80 | 2.99 | 1.64 | 5.46 | 0.009 | 2.97 | 1.63 | 5.43 | 0.01 | 2.98 | 1.63 | 5.45 | 0.009 |
| >80 | 3.79 | 1.81 | 7.94 | 0.005 | 3.76 | 1.79 | 7.88 | 0.005 | 3.78 | 1.80 | 7.92 | 0.005 |
| rs1229984 (ref = TT genotype) | ||||||||||||
| TC genotype | 0.90 | 0.65 | 1.24 | 0.04 | 0.89 | 0.65 | 1.24 | 0.04 | ||||
| CC genotype | 1.7 | 1.03 | 2.70 | 0.02 | 1.66 | 1.03 | 2.70 | 0.018 | ||||
| rs671 (ref = GG genotype) | ||||||||||||
| GA genotype | 0.86 | 0.63 | 1.18 | 0.97 | 0.86 | 0.63 | 1.17 | 0.97 | ||||
| AA genotype | 0.75 | 0.40 | 1.40 | 0.49 | 0.75 | 0.40 | 1.39 | 0.49 | ||||