. 2022 Jun 6;12(1):747–759. doi: 10.1002/cam4.4920

TABLE 6.

Association between ADH1B and ALDH2 polymorphisms and the risk of cancers

Variable	rs1229984_TT & rs671_GA/AA(n = 11,244)			p value ^a	rs1229984_TC/CC & rs671_GG(n = 1585)			p value ^a	rs1229984_TC/CC & rs671_GA/AA(n = 1415)			p value ^a
Variable	OR	95% CI		p value ^a	OR	95% CI		p value ^a	OR	95% CI		p value ^a
Age (ref = <40)
41–60	1.00	0.93	1.08	0.81	0.95	0.82	1.11	0.33	1.05	0.89	1.24	0.63
61–80	0.98	0.91	1.06	0.41	0.83	0.71	0.97	0.07	1.05	0.89	1.23	0.67
>80	1.01	0.89	1.14	0.78	0.86	0.66	1.11	0.51	1.00	0.77	1.31	0.81
Gender (ref = Female)
Male	0.99	0.94	1.04	0.57	0.95	0.86	1.06	0.36	0.93	0.83	1.03	0.17
Cancer of larynx, pharynx, and nasal cavities	1.19	0.96	1.47	0.11	1.41	0.96	2.08	0.08	2.00	1.41	2.85	0.0001
Cancer of esophagus	0.92	0.54	1.55	0.74	3.02	1.54	5.91	0.001	4.81	2.65	8.75	<0.0001
Cancer of pancreatic	0.75	0.50	1.13	0.17	1.09	0.52	2.30	0.82	1.84	0.99	3.45	0.06

Note: Control is ADH1B rs1229984 and ALDH2 rs671 wild‐type (n = 11,899).

^{^a}

Using a univariable logistic regression to compare variables between ADH1B rs1229984 and ALDH2 rs671 variants.