TABLE 1.
Time p.i. (h) | Yield of chlamydiae (mean log 10 IFU ± 1 SD)
|
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---|---|---|---|---|---|---|
C. trachomatis L3
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C. trachomatis MoPn
|
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Nramp1d mice | Wild-type mice | HeLa cells | Nramp1d mice | Wild-type mice | McCoy cells | |
0a | 4.69 ± 0.10 | 4.69 ± 0.10 | 4.69 ± 0.10 | 5.28 ± 0 | 5.28 ± 0 | 5.28 ± 0 |
5 | 3.58 ± 0.25 | 3.43 ± 0.40 | 2.80 ± 0 | 2.46 ± 0.09 | 2.60 ± 0.2 | 2.93 ± 0 |
24 | 4.01 ± 0.08 | 4.02 ± 0.26 | 7.68 ± 0.5 | 5.87 ± 0.02 | 6.36 ± 0.08 | 6.14 ± 0 |
48 | 5.73 ± 0.14 | 5.64 ± 0.23 | 8.71 ± 0.05 | 6.34 ± 0.06 | 6.28 ± 0.09 | 8.12 ± 0 |
72 | 5.69 ± 0.17 | 5.06 ± 0.05 | 8.55 ± 0.07 | 6.71 ± 0.29 | 6.49 ± 0.09 | 6.63 ± 0 |
For 0 h, values are numbers of C. trachomatis IFU used to infect the macrophages.