Fig 1. Relative luciferase activity (RLA) in Vero cells.

Different transfection experiments were performed independently with miRNA mimic, or miRNA inhibitor or scramble control. Each experiment was repeated at least 3 times and conducted in triplicate; the results presented in the figures indicate the median values obtained and 25^th-75^th percentile. RLA were measured in Vero cells 24 hours after transfection with (a) miR-23a-3p mimic, or inhibitor, or scramble negative control; (b) miR-181a-5p mimic, or inhibitor or scramble negative control; (c) miR-27b-3p mimic, or inhibitor or scramble negative control. RLA of cells transfected with miR-23a-3p inhibitor was significantly higher compared to that observed in cells transfected with miR-23a-3p mimic or scramble negative control; RLA of cells transfected with miR-181a-5p was significantly lower compared to that observed in cells transfected with miR-181a-5p mimic or scramble negative control. No differences were observed regarding miR-27b-3p mimic or inhibitor transfection. ns: not significative.