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PPI network, modules, and identification of 5 hub genes. (a) The PPI network of the 94 DETFs and 111 DEIRGs (interaction score > 0.9). Blue nodes represent transcription factors, and green nodes represent immune-related genes. (b) The correlation of DETFs and DEIRGs (P < 0.001). (c) Venn diagram showing the overlap of the top ten nodes in topological features of degree, betweenness, and closeness.
