Table 2.
Correlations between the expression level of IGFBP3 and clinicopathological factors in ABC-DLBCL patients from the GEO database.
| Variables | Expression level of IGFBP3 | p value | ||
|---|---|---|---|---|
| Low | High | |||
| Age | 0.159 | |||
| ≤60 | 20 | 28 | ||
| >60 | 53 | 45 | ||
|
| ||||
| Sex | 0.238 | |||
| Female | 33 | 26 | ||
| Male | 40 | 47 | ||
|
| ||||
| Stage | 0.020 | |||
| I-II | 25 | 39 | ||
| III-IV | 48 | 34 | ||
|
| ||||
| Extranodal infiltration | 0.033 | |||
| ≤1 | 50 | 61 | ||
| >1 | 23 | 12 | ||
|
| ||||
| ECOG score | 0.442 | |||
| ≤1 | 53 | 57 | ||
| >1 | 20 | 16 | ||
|
| ||||
| LDH | 0.011 | |||
| Normal | 22 | 37 | ||
| Elevated | 51 | 36 | ||
|
| ||||
| IPI score | 0.007 | |||
| ≤2 | 36 | 52 | ||
| >2 | 37 | 21 | ||
|
| ||||
| Treatment response | 0.706 | |||
| CR | 53 | 55 | ||
| Non-CR | 20 | 18 | ||
ECOG, eastern cooperative oncology group performance status; LDH, lactate dehydrogenase; IPI, international prognostic index; CR, complete response; non-CR, partial response, stable disease, progressive disease; bold, significant difference.