Table 2.

Different liver diseases and liver functional reserve.

Subgroup	Proportion	No. of studies	No. of patients	Estimates (HR)	Lower limit to Upper limit	P‐value
Cirrhosis
All cirrhosis	100%	5	641	2.61	1.76–3.86	< 0.001
Proportion > median	62.67–100%	8	1130	2.47	1.77–3.43	< 0.001
Proportion < median	21.58–61.43%	9	2120	1.72	1.46–2.03	< 0.001
ALD
Proportion > median	16.67–47.5%	9	1132	1.53	1.23–1.91	< 0.001
Proportion < median	3.26–15.52%	9	966	1.84	1.50–2.26	< 0.001
NASH
Proportion > median	11.46–100%	5	541	1.67	1.30–2.15	< 0.001
Proportion < median	6.7–10.1%	5	687	1.79	1.44–2.22	< 0.001
HBV
proportion > median	25.1–85.18%	15	2515	1.64	1.36–1.98	< 0.001
proportion < median	6.59–20.18%	18	3662	2.01	1.69–2.37	< 0.001
HCV
Proportion > median	39.19–100%	18	3641	2.07	1.71–2.50	< 0.001
Proportion < median	6.86–38.18%	16	2174	1.78	1.45–2.18	< 0.001
Child–Pugh class A
Proportion > median	80.7–100%	17	3157	1.61	1.44–1.81	< 0.001
Proportion < median	50–78.66%	18	3790	2.27	1.83–2.81	< 0.001
Child–Pugh class B
Proportion > median	22.75–62.67%	16	3550	2.17	1.75–2.69	< 0.001
Proportion < median	2.15–16.67%	15	3056	1.64	1.45–1.84	< 0.001

AH alcohol-related liver disease, NASH nonalcoholic steatohepatitis, HBV hepatitis B Virus, HCV hepatitis C Virus.