Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jan 17;13:886. doi: 10.1038/s41598-022-27152-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Identification of drugs mimicking or counteracting the differential expression pattern in cluster 3 during wound healing. (A) The similarity between the DEGs between cluster 3 cells in wounded skin and cluster 3 cells in normal skin with log2FC ± 0.25 were checked with the signature of each of the 6,100 drug/ compound instances in the Connectivity Map database. (B) The top identified drugs having signature that mimics the differential expression pattern in cluster 3 in wounded skin (positive enrichment). (C) The top identified drugs having signature that counteracts the differential expression pattern in cluster 3 in wounded skin (negative enrichment).