Table 3.
Multiple logistic regression analysis demonstrating factors (including total infusions) associated with low or high NRS
| Postoperative within 24 h | Postoperative 24–48 h | |||
|---|---|---|---|---|
| No paina/mild painb | No paina/moderate to severe painc | No paina/mild painb | No paina/moderate to severe painc | |
| Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) | |
| Age | 1.001 (0.993–1.010) | 0.987 (0.976–0.997)* | 0.996 (0.989–1.003) | 0.997 (0.986–1.007) |
| Weight | 1.001 (0.993–1.009) | 1.009 (0.999–1.019) | 1.003 (0.996–1.009) | 1.001 (0.991–1.011) |
| Gender | ||||
| Male | Ref | Ref | Ref | Ref |
| Female | 1.585 (1.263–1.989)* | 1.342 (1.023–1.760)* | 1.422 (1.171–1.726)* | 1.084 (0.832–1.412) |
| Surgical mode | ||||
| Non-lumpectomy | Ref | Ref | Ref | Ref |
| Lumpectomy | 1.191 (0.926–1.532) | 1.259 (0.939–1.688) | 1.456 (1.159–1.829)* | 1.573 (1.172–2.109)* |
| Systematic classification of surgical sites | ||||
| Digestive system | Ref | Ref | Ref | Ref |
| Urinary system | 0.330 (0.242–0.450)* | 0.113 (0.072–0.179)* | 0.432 (0.325–0.573)* | 0.233 (0.144–0.377)* |
| Reproductive system | 0.372 (0.281–0.494)* | 0.141 (0.099–0.201)* | 0.471 (0.372–0.596)* | 0.188 (0.129–0.274)* |
| Respiratory system | 1.289 (0.870–1.910) | 2.077 (1.392–3.100)* | 1.247 (0.906–1.716) | 1.982 (1.381–2.847)* |
| Blood circulatory system | 0.578 (0.324–1.030) | 0.276 (0.136–0.557)* | 0.613 (0.376–1.000) | 0.248 (0.107–0.576) |
| Other systems | 0.378 (0.288–0.495)* | 0.187 (0.135–0.260)* | 0.505 (0.396–0.646)* | 0.269 (0.188–0.385)* |
| Medication classification | ||||
| Sufentanil | Ref | Ref | Ref | Ref |
| Non-sufentanil | 0.924 (0.697–1.226) | 0.727 (0.517–1.022) | 0.873 (0.695–1.096) | 0.688 (0.491–0.965)* |
| Total volume of infusion (within 24 h after operation) | ||||
| ≤ 27 ml | Ref | Ref | – | – |
| 28–34 ml | 1.042 (0.827–1.313) | 1.022 (0.759–1.375) | – | – |
| 35–43 ml | 1.025 (0.816–1.289) | 1.253 (0.939–1.673) | – | – |
| > 43 ml | 1.404 (1.064–1.853)* | 2.830 (2.037–3.934)* | – | – |
| Total volume of infusion (24–48 h after operation) | ||||
| ≤ 30 ml | – | – | Ref | Ref |
| 31–37 ml | – | – | 0.945 (0.777–1.150) | 0.968 (0.703–1.332) |
| 38–46 ml | – | – | 1.160 (0.945–1.425) | 1.331 (0.967–1.833) |
| > 46 ml | – | – | 1.258 (1.008–1.571)* | 3.024 (2.199–4.159)* |
Analyses were based on multiple logistic regression. Multiple logistic regression analysis of factors associated with low or high NRS within 24 h and 48 h postoperatively, with model containing seven variables: age, gender, weight, surgical mode, systematic classification of surgical sites, medication classification, and total volume of infusion
OR odds ratio, CI confidence interval, NRS Numerical Rating Scale
*Statistically significant results
aNRS 0/10
bNRS 1–3/10
cNRS ≥ 4/10