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. 2022 Dec 19;10:rbac105. doi: 10.1093/rb/rbac105

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© The Author(s) 2022. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — In vitro bioprinted microenvironment for sweat gland regeneration. (A) Schematic of the printing process with epidermal progenitors and ECM incorporated in composite hydrogels to mimic the microenvironment for sweat gland regeneration. (B) The graphic illustration of 3D-bioprinted matrix directed MSC differentiation. CTHRC1 is the main biochemical cues during SG development, and structural cues up-regulated the expression of Hmox1 synergistically initiated branching morphogenesis of SG. Adapted with permission from Huang et al. and Yao et al. [24, 153].