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. 2023 Jan 4;13:1071868. doi: 10.3389/fphar.2022.1071868

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Copyright © 2023 Yu, Li, Lin, Zhu, Hao, Wu, Sun, Yang and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic diagram of the silk structure. (A) heavy chain (i.e., N-terminus, β-sheets, Amorphous and C-terminus). and light chain which linked via disulphide bonds. (B) silkworm thread, fibril overall structure and silk fibroin polypeptide chains. Notes: Sun, W., Gregory, D.A., Tomeh, M.A., Zhao, X., 2021. Silk fibroin as a functional biomaterial for tissue engineering. International Journal of Molecular Sciences 22, 1499. Reprinted with permission from references. Copyright 2021, MDPI.