Table 3.
Comparing the mean values of the five clinical parameters measured in this study 1 year before switching from reslizumab to mepolizumab to the mean values of the same parameters 6 months after switching.
Clinical Parameter Mepolizumab n = 8 | 1-year pre switch, Mean (SD) | 6 months post switch, Mean (SD) | p-value |
---|---|---|---|
Hospital admissions(adjusted) | 0.06 (0.18) | 0 | 0.33 |
Exacerbations | 0.44 (0.62) | 0.13 (0.36) | 0.24 |
Maintenance OCS dose (mg) | 2.5 (5.18) | 2.5 (5.18) | – |
FEV1 (%), n = 7 | 78.8 (26.4) | 67.6 (28.8) | 0.02 |
ACQ score | 1.6 (1.6) | 1.5 (1.4) | 0.43 |