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. 2023 Jan 4;9:1038273. doi: 10.3389/fcvm.2022.1038273

Table 2.

Differentially expressed metabolites between the model and HJ11 groups.

Group
Class Metabolite Model HJ11 P
Alcohols Octadecanol 2.23 ± 0.80 6.64 ± 2.86 0.0043
1-Hexadecanol 2.20 ± 0.64 4.79 ± 1.56 0.0076
Erythritol 3.32 ± 2.72 1.82 ± 1.01 0.0411
Alkylamines Spermidine 12.67 ± 6.94 2.96 ± 1.14 0.0086
5-Methoxytryptamine 2.23 ± 1.32 0.84 ± 0.47 0.0259
3-Amino-2-piperidone 14.61 ± 5.01 8.42 ± 0.54 0.0411
Amino Acids Lysine 206.87 ± 37.19 121.68 ± 11.87 0.0022
Isoleucine 107.09 ± 56.26 57.15 ± 12.59 0.0086
3-Cyanoalanine 1.16 ± 0.65 0.37 ± 0.17 0.0086
Alanine 252.58 ± 95.64 162.42 ± 18.96 0.0151
Asymmetric dimethylarginine 25.34 ± 6.20 17.07 ± 2.36 0.0206
Cysteine 5.59 ± 1.59 3.50± 1.04 0.0261
Valine 177.24 ± 73.04 106.62 ± 33.74 0.0411
4-Hydroxyproline 4.68 ± 1.69 2.78 ± 0.97 0.0434
Bile acids Lithocholic acid 12.93 ± 5.98 22.21 ± 6.03 0.0232
Carbohydrates Glucaric acid 0.63 ± 0.23 1.09 ± 0.24 0.0069
1,5-Anhydroglucitol 15.43 ± 6.96 24.43 ± 3.81 0.0247
Gluconic acid 1.49 ± 2.92 0.14 ± 0.09 0.0411
Sucrose 2.90 ± 1.91 0.99 ± 1.30 0.0411
Turanose 4.66 ± 2.68 2.40 ± 3.61 0.0411
Carboxylic acids and derivatives gly_pro 4.71 ± 1.95 2.51 ± 1.02 0.0411
Fatty acids Arachidic acid 44.43 ± 22.09 129.35 ± 89.41 0.0151
Nonadecanoic acid 3.23 ± 0.99 5.7 ± 2.00 0.0290
Heptadecanoic acid 23.48 ± 11.51 52.6 ± 23.66 0.0292
Linoleic acid 136.38 ± 23.69 99.86 ± 28.00 0.0355
Indoles Indolelacetic acid 2.58 ± 2.09 0.69 ± 1.02 0.0259
5-Hydroxyindoleacetic acid 9.14 ± 6.20 2.73 ± 1.98 0.0259
Lipids Lathosterol 8.62 ± 1.76 4.45 ± 2.09 0.0086
Nucleotides Pseudouridine 1.59 ± 0.94 4.29 ± 1.82 0.0086
Xanthine 3.17 ± 1.45 11.82 ± 8.09 0.0151
Organic acids Methylphosphate 9.33 ± 6.12 53.34 ± 12.32 8.13E-05
3-Methyl-2-oxopentanoic acid 2.48 ± 1.03 8.39 ± 3.09 0.0022
3,4-Dihydroxybutyric acid 1.57 ± 0.79 0.91 ± 0.43 0.0411
Phenylpropanoids Caffeic acid 0.88 ± 0.25 1.39 ± 0.21 0.0040
Vitamins δ-Tocopherol 0.44 ± 0.09 0.67 ± 0.16 0.0171