Table 1.
Effect of H. scabra extracts on lifespan of CL2006, CL4176 and CL2355 worms.
| Strain + treatment | % increase | Mean ± SD | Max | P value |
|---|---|---|---|---|
| CL2006 + 0.1% DMSO | – | 8.75 ± 2.60 | 14 | – |
| CL2006 + 500 μg/ml WBEA | 11.40 | 9.75 ± 3.37∗∗ | 18 | <0.01 |
| CL2006 + 500 μg/ml WBBU | 13.03 | 9.89 ± 3.70∗∗ | 19 | <0.01 |
| CL2006 + 500 μg/ml BWEA | 12.22 | 9.82 ± 3.37∗∗ | 19 | <0.01 |
| CL2006 + 500 μg/ml BWBU | 6.17 | 9.29 ± 3.50∗∗ | 18 | <0.01 |
| CL2006+ ddH2O | – | 8.72 ± 2.70 | 14 | – |
| CL2006 + 500 μg/ml BWET | 4.82 | 9.13 ± 3.07∗∗ | 15 | <0.01 |
| CL2006 + 50 μM TET | 13.77 | 9.91 ± 3.94∗∗ | 20 | <0.01 |
| CL4176 + 0.1%DMSO | – | 7.85 ± 2.22 | 11 | – |
| CL4176 + 500 μg/ml WBEA | 36.94 | 10.75 ± 2.65∗∗ | 15 | <0.01 |
| CL4176 + 500 μg/ml WBBU | 16.81 | 9.17 ± 2.50∗∗ | 14 | <0.01 |
| CL4176 + 500 μg/ml BWEA | 17.45 | 9.22 ± 2.40∗∗ | 13 | <0.01 |
| CL4176 + 500 μg/ml BWBU | 8.15 | 8.49 ± 2.53 | 13 | 0.1806 |
| CL4176+ ddH2O | – | 7.40 ± 2.20 | 11 | – |
| CL4176 + 500 μg/ml BWET | 22.16 | 9.04 ± 2.20∗∗ | 13 | <0.01 |
| CL4176 + 50 μM TET | 34.05 | 9.92 ± 2.90∗∗ | 15 | <0.01 |
| CL2355 + 0.1%DMSO | – | 5.96 ± 1.6 | 10 | – |
| CL2355 + 500 μg/ml WBEA | 31.70 | 7.85 ± 2.39∗∗ | 16 | <0.01 |
| CL2355 + 500 μg/ml WBBU | 18.12 | 7.04 ± 2.00∗∗ | 12 | <0.01 |
| CL2355 + 500 μg/ml BWEA | 28.69 | 7.67 ± 2.48∗∗ | 15 | <0.01 |
| CL2355 + 500 μg/ml BWBU | 21.97 | 7.27 ± 2.36∗∗ | 14 | <0.01 |
| CL2355+ ddH2O | – | 6.38 ± 1.78 | 10 | – |
| CL2355 + 500 μg/ml BWET | 6.73 | 6.81 ± 2.03 | 12 | 0.0147 |
| CL2355 + 50 μM TET | 19.12 | 7.60 ± 2.81∗∗ | 17 | <0.01 |