Table 2.

Cumulative incidence of liver-related events stratified based on non-invasively assessed clinically significant portal hypertension status

Category	No. of events (cumulative incidence %) at 3-year
	Liver decompensation*	Liver-related events†	All-cause death†
CSPH excluded (n=140)	0 (0.0)	7 (5.0)	2 (1.4)
Grey-zone (n=592)	10 (2.6)	43 (11.3)	11 (2.9)
Low probability of CSPH	8 (3.7)	21 (10.0)	9 (4.2)
High probability of CSPH
CSPH (n=427)	59 (13.8)	82 (19.2)	25 (5.8)

Definition of CSPH category: CSPH, defined as liver stiffness measurement (LSM) ≥25 kPa; CSPH excluded, defined as LSM <15 kPa and platelet count ≥150; grey-zone, patients who did not fulfilled non-invasive criteria to diagnose or exclude CSPH; high probability of CSPH, defined as LSM 20–25 kPa & platelet count <150, or LSM 15–20 kPa & platelet count <110×109/L; low probability of CSPH, other patients within the grey zone.

CSPH, clinically significant portal hypertension.

^*Cumulative incidence was calculated based on competing risks regression for clustered data with hepatocellular carcinoma and death as competing risks.

^†Cumulative incidence was calculated based on Cox regression with shared frailty.