Table 6.
HRV and clinical prediction model, n = 101 infants.
| OR (95% CI) | p value | AUROC (95% CI) | |
|---|---|---|---|
| Mean NN (ms)a | 2.34 (1.07–5.10) | 0.032 | 0.895 (0.832–0.958) |
| HF power (ms2)a | 1.94 (0.47–7.99) | 0.361 | |
| LF/HF ratiob | 1.51 (0.47–4.89) | 0.488 | |
| TINN (ms)b | 0.70 (0.19–2.58) | 0.595 | |
| MSE Complexity Indexa | 0.84 (0.38–1.84) | 0.661 | |
| MSE short-scale slopea | 0.35 (0.13–0.98) | 0.045 | |
| Suspected foetal distress in labour (yes) | 0.30 (0.04–2.20) | 0.237 | |
| Gestational age (weeks) | 0.76 (0.48–1.22) | 0.251 | |
| Mode of delivery (emergency) | 0.63 (0.12–3.29) | 0.583 | |
| Apgar scores at 5 min | 0.94 (0.72–1.23) | 0.654 | |
| Assisted ventilation at 10 min of age (yes) | 8.94 (1.86–43.00) | 0.006 |
HRV variable was standardised prior to conducting the logistic regression.
HRV variable was log transformed (log base 10) and then standardised prior to conducting the logistic regression.
The multivariable model is: log[p/(1-p)] = 11.49 + 0.85 (standardised Mean NN) + 0.66 (standardised log 10 HF power) + 0.42 (standardised log 10 LF/HF ratio) – 0.35 (standardised log 10 TINN)-0.18 (standardised MSE c index) −1.04 (standardised MSE slope short) −1.20 (suspected foetal distress in labour)-0.28 (GA at delivery) −0.46 (emergency delivery) – 0.06 (Apgar score at 5 min) + 2.19 (assisted ventilation) p = 0.548 for Hosmer-Lemeshow goodness of fit.
HRV, Heart Rate Variability; NN interval, normalised RR interval; HF power, high frequency power (0.15–0.4 Hz), LF/HF ratio, low frequency/high frequency ratio; TINN, triangular interpolation of the NN interval histogram; MSE, multiscale entropy.