Table 7.
Subgroup analysis of infants undergoing therapeutic hypothermia - HRV and clinical prediction model, n = 52 infants.
| OR (95% CI) | p value | AUROC (95% CI) | |
|---|---|---|---|
| Mean NN (ms)a | 1.72 (0.50–5.86) | 0.386 | 0.864 (0.766–0.963) |
| LF/HF rateb | 1.70 (0.49–5.90) | 0.401 | |
| TINN (ms)b | 1.16 (0.43–3.12) | 0.769 | |
| MSE short-scale slopea | 0.27 (0.06–1.30) | 0.102 | |
| MSE maximuma | 1.88 (0.44–8.01) | 0.395 | |
| Suspected foetal distress in labour (yes) | 0.11 (0.00–2.77) | 0.178 | |
| Gestational age (weeks) | 0.80 (0.38–1.69) | 0.562 | |
| Mode of delivery (emergency) | 3.19 (0.17–58.73) | 0.434 | |
| Gender (male) | 1.54 (0.29–8.06) | 0.608 | |
| Apgar scores at 5 min | 0.79 (0.51–1.22) | 0.289 | |
| Assisted ventilation at 10 min of age (yes) | 4.03 (0.28–58.46) | 0.307 | |
| Cord pH | 0.01 (0.00–2.37) | 0.103 | |
| Base deficit | 0.97 (0.79–1.19) | 0.741 |
a
HRV variable was standardised prior to conducting the logistic regression.
b
HRV variable was log transformed (log base 10) and then standardised prior to conducting the logistic regression.
HRV, Heart Rate Variability; NN interval, normalised RR interval; LF/HF ratio, low frequency/high frequency ratio; TINN, triangular interpolation of the NN interval histogram; MSE, multiscale entropy.