Table 10.

Guideline Recommendations for juvenile myelomonocytic leukaemia.

Juvenile myelomonocytic leukaemia
No	Recommendations	Strength
1	At this time the increased risk for JMML in NF1 is not clear, and is almost certainly <1%. As such specific clinical assessment probably should not be conducted.	moderate
2	Observing juvenile xanthogranulomas in children with NF1 may raise awareness to actively search for other alarming signs of JMML (amongst others hepatosplenomegaly, paleness, abnormal lymph nodes), but should not be considered reason enough for extensive investigations for JMML.	weak

Note. JMML = juvenile myelomonocytic leukaemia; NF1 = Neurofibromatosis type 1.