Table 12.

Guideline Recommendations for phaeochromocytoma and paraganglioma.

Phaeochromocytoma and paraganglioma
No	Recommendations	Strength
1	Routine biochemical screening for phaeochromocytoma and paraganglioma is not recommended in people with NF1 except for all women with NF1 who are contemplating pregnancy or are already pregnant.	moderate
2	Biochemical testing for phaeochromocytoma and paraganglioma should be conducted in any person with NF1 who has raised blood pressure unexplained by other medical reason.	moderate
3	Biochemical testing for phaeochromocytoma and paraganglioma might be considered prior to any elective surgical procedures requiring general anaesthesia in adult patients with NF1.	weak
4	As in any phaeochromocytoma and paraganglioma predisposition syndrome surgery should be considered for symptomatic or biochemically active lesions.	strong
5	A cortical-sparing adrenalectomy should be the preferred approach due to the risk of metachronous contralateral adrenal tumour.	moderate

Note. NF1 = Neurofibromatosis type 1.