Table 6.

Guideline Recommendations for cutaneous neurofibroma.

Cutaneous neurofibroma
No	Recommendations	Strength
1	Clinical assessment consisting of visual inspection and palpation should begin when NF1 is diagnosed and should be repeated at every clinical visit.	strong
2	Discomfort for the patient should be the primary indication for treatment. With regard to aesthetic considerations the impacts are unique to each individual and each health system has its own criteria and thresholds for intervention, so this should be considered on a case-by-case with discussion between the treating team and person with NF1.	weak
3	Removal should be by laser, surgery, electrodessication or radiofrequency ablation. If multiple tumours are removed, histological assessment of all clinically obvious small cutaneous neurofibroma is not necessary.	moderate
4	Given the burden of the visible manifestations in NF1 with cutaneous neurofibroma, patients with cutaneous neurofibroma should be offered psychological support (please see recommendations in the psychosocial needs, Table 15).	weak

Note. NF1 = Neurofibromatosis type 1.