Table 1.
General characteristics of the population reviewed. HT: Arterial Hypertension; DM: Diabetes Mellitus; COPD: chronic obstructive pulmonary disease; CKD: Chronic Kidney disease; HF: Heart failure; FW: Follow-up; NR: Not reported. *Defined as Chronic Pulmonary disease; **Only DM type 2. R: Retrospective
| Authors | Study Design | Sample size n |
Cases n |
Controls n |
Age (years) |
Males n (%) |
HT n (%) |
DM n (%) |
COPD n (%) |
CKD n (%) |
Obesity n (%) |
HF n (%) |
Cancer n (%) |
Cerebrovascular disease n (%) |
FW-length (months) | NOS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cohen et al. [14] | R | 2.895.943 | 133,366 | 2,762,577 | 75.7 |
1.227.545 (42.0) |
2.081.772 (72.0) |
938.043 (32.7) |
578.650 (20)* |
528.314 (14.0) |
478.902 (17.0) |
334,654 (12) |
418.700 (14.4) |
364.782 (13.0) |
4 | 8 |
| Wang et al. [15] | R | 2.940.988 | 691,455 | 2,249,533 | 43.8 |
1.241.483 (42.2) |
440.998 (14.9) |
188.488 (6.4)** |
51,592 (1.7) |
59,177 (2.0) |
286,338 (9.7)** |
NR | NR | NR | 12 | 7 |
| Xie et al. [16] | R | 5.791.407 | 153,760 | 5,637,647 | 62.5 |
5.228.431 (90.2) |
1.525.944 (26.3) |
1.321.907 (22.8) |
633.000 (10.9) |
970.057 (16.7) |
2.462.44 (42.5) |
NR |
357.192 (6.1) |
NR | 12 | 8 |
| Daugherty et al. [17] | R | 9.247.505 | 266,586 | 8,980,919 | 42.4 |
4.640.393 (50.2) |
NR |
521.699 (5.6) |
NR | NR | NR | NR | NR | NR | 6 | 6 |
| Kompaniyets et al. [18] | R | 3.125.676 | 781,419 | 2,344,257 | 12 |
1.709.108 (54.6) |
NR | NR | NR | NR | NR | NR | NR | NR | 12 | 5 |
| Al-Aly et al. [19] | R | 5.017.431 | 33,940 | 4,983,491 | 64.9 |
4.512.549 (89.9) |
NR | 1.275.370 | NR |
423.329 (8.4) |
NR | NR |
371.526 (7.4) |
288.266 (5.7) |
6 | 7 |