Table 6.
Whole blood trace element and toxic metal concentrations in epileptic and healthy dogs.
|
Blood element (ng/g) Reference values from literature |
Epileptic (n = 19) Mean ±SD (min–max) |
Healthy (n = 19) Mean ±SD (min–max) |
P |
|---|---|---|---|
| Cu 483.79 ± 59.04 (349.70–614.20)a |
511.95 ± 40.44 (449–601) | 463.20 ± 55.17 (380–565) | 0.007** |
| Zn 3685.56 ± 542.69 (2850–5630)a |
3780.53 ± 341.10 (3120–4360) | 4158.42 ± 1380.98 (2990–8420) | 0.86 |
| Cu/Zn ratio | 0.14 ± 0.02 (0.10–0.16) | 0.12 ± 0.03 (0.06–0.16) | 0.04* |
| Se 388.14 ± 40.95 (310.10–476.60)a |
488.53 ± 47.69 (358–569) | 393.90 ± 51.89 (278–458) | <0.001*** |
| Cr 3.67 ± 6.07 (1.06–24.83)a |
1.23 ± 0.73 (1.06–4.25) | 5.16 ± 7.25 (1.06–23.49) | 0.01* |
| Mn 30.84 ± 9.78 (14.50–59.50)a |
34.64 ± 11.75 (18.90–60.50) | 36.19 ± 9.62 (21.24–59.53) | 0.51 |
| Fe 605382.98 ± 62129.09 (486000–742000)a |
625368.42 ± 55588.98 (510000–780000) | 599526.32 ± 62726.36 (508000–713000) | 0.12 |
| As 1.15 ± 1.09 (0.04–4.30)a |
2.65 ± 4.09 (0.50–18.10) | 1.33 ± 1.20 (0.12–4.27) | 0.30 |
| Cd 0.03 ± 0.01 (0.01–0.06)a |
0.02 ± 0.02 (0.01–0.09) | 0.03 ± 0.03 (0.01–0.13) | 0.10 |
| Hg 0.53 ± 0.35 (0.12–1.61)a |
0.94 ± 1.58 (0.11–7.29) | 0.46 ± 0.33 (0.12–1.14) | 0.18 |
| Pb 3.50 ± 2.72 (0.28–12.37)a |
2.17 ± 1.80 (0.32–6.51) | 2.88 ± 2.07 (0.28–8.04) | 0.22 |
*Correlation is significant at the 0.05 level, **at the 0.01 level and, ***at the 0.001 level (all 2-tailed). aRosendahl et al. (25), mean± SD (min-max).