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. 2023 Jan 4;12:1080054. doi: 10.3389/fonc.2022.1080054

Table 4.

Changes in metabolic parameters before and after NAC.

Variable Pre-NAC Post-NAC t/Z P
Height (cm) 160.102 ± 5.322
Weight (kg) 62.887 ± 9.260 63.991 ± 9.389 -1.245 0.214
BMI (kg/m2) 24.524 ± 3.309 24.956 ± 3.370 -1.362 0.174
FBG (mmol/L) 5.300 (4.800-5.800) 5.400 (4.950-5.900) -1.880 0.060
TG (mmol/L) 1.140 (0.785-1.550) 1.730 (1.245-2.490) -8.054 <0.001
TC (mmol/L) 4.693 ± 0.961 5.172 ± 1.053 -5.002 <0.001
HDL-C (mmol/L) 1.620 ± 0.401 1.503 ± 0.392 3.101 0.002
LDL-C (mmol/L) 3.135 ± 0.890 3.572 ± 0.906 -5.121 <0.001
SBP (mmHg) 124.411 ± 20.237 126.883 ± 17.612 -1.369 0.172
DBP (mmHg) 75.813 ± 11.901 76.706 ± 12.441 -0.771 0.441
No. of MetS components 1.440 ± 1.308 2.030 ± 1.321 -4.704 <0.001

NAC, neoadjuvant chemotherapy; BMI, body mass index; FBG, fasting blood glucose; TG, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C; low-density lipoprotein cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; MetS, metabolic syndrome.