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. 2023 Jan 4;13:1074044. doi: 10.3389/fimmu.2022.1074044

Figure 1.

Figure 1

Effect of belimumab treatment on SLE disease activity, attainment of therapeutic goals and dose of glucocorticoids. (A, B) Violin plots of SLEDAI-2K (A) and PGA (B) values at consecutive time-points during belimumab treatment. Blue lines represent median values. The non-parametric Skillings-Mack test was used to determine the statistical significance of longitudinal trends. The number of analysed patients were 178, 164, 136, 109, 74 and 48 at the 3, 6, 9, 12, 18 and 24-month time points, respectively. The number of patients with shorter follow-up were 0, 6, 16, 21, 40 and 53, respectively. (C) Rates (Lundex-corrected) of attainment of low disease activity (LLDAS (30)), remission (according to the DORIS (31) and the Zen et al. (32, 33) definitions) in belimumab-treated patients. (D) Stacked bars demonstrating the glucocorticoid dosage level (none, >0 and ≤5 mg/day, >5 to ≤7.5 mg/day, >7.5 mg/day prednisone equivalent) in patients under treatment with belimumab.