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. 2023 Jan 4;13:1020822. doi: 10.3389/fimmu.2022.1020822

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Copyright © 2023 Zhang, Xie, Zhou, Li, Ning, Su, Ye, Ai, Lai, Pan, Liu, Liao, Su, Li, Liang, Cui and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Composition of gut microbiota at different stages of HIV infection. (A) PCoA of Bray-Curtis dissimilarity of microbiota revealed that gut microbiota was separated by different stages of HIV infection, and a statistically significant difference was observed in the PERMANOVAR (P=0.001); (B) PLS-DA showed that gut microbiota at different stages of HIV infection clustered into three distinct clusters. Each dot refers to a sample. Red dot, yellow dot and green dot represent AIDS group, pre-AIDS group and healthy control group respectively.