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Cellular homeostasis regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Post-translational modifications regulate a wide range of proteins to enable appropriate transcription and maintain cellular function. HATs and HDACs are integral to this process by adding or removing acetyl groups to/from histone or non-histone proteins, thus changing chromatin accessibility, or protein structure, function, or half-life.
