Table 1.
Cross-sectional surveys investigating the relationship between adult Opisthorchis viverrini worm burden and faecal egg counts in humans included in the analysis. Surveys TH1–4 and LAO1 had individual-level data used for model fitting. Surveys TH5 and LAO2–3 had aggregated data used for model validation. The table shows the method of adult worm collection, either from liver examination during autopsy or expulsion with a saline purgative after anthelmintic treatment with praziquantel; the study location and date; the number of human participants (sample size); the arithmetic mean number of O. viverrini adult worms recovered; and the diagnostic method used for parasite egg identification and counting. TH relates to surveys in Thailand and LAO to Laos.
survey and method | location and year(s) | sample size | worms recovered |
faecal egg diagnostic | ||
---|---|---|---|---|---|---|
mean | range | s.d.a | ||||
TH1 autopsy [34] | Khon Kaen 1982–1999 | 139 | 160 | 0–2954 | 390 | FECTb |
TH2 expulsion [35] | Khon Kaen 1987 | 33 | 85 | 0–565 | 154 | Stoll’s dilution |
TH3 expulsion [31] | Kalasin 1989 | 231 | 39 | 0–832 | 105 | FECTb |
TH4 expulsion [36] | Khon Kaen 1991 | 141 | 49 | 0–874 | 102 | FECTb |
LAO1 expulsion [37] | Savannakhet 2005 | 97 | 183 | 0–2178 | 286 | FECTb |
TH5 autopsyc [38] | Khon Kaen 1966 | 9 | 2588 | 20–11856 | NAd | Stoll’s dilution |
LAO2 expulsionc [39] | Savannakhet 2008 | 125 | 11 | 0–111 | 29 | Kato–Katz |
LAO3 expulsionc [39] | Savannakhet 2011 | 82 | 3 | 0–66 | 9 | Kato–Katz |
aStandard deviation.
bFormalin–ether concentration technique.
cSurvey used for validation only.
dData not available.