Figure 8.
Relationship between the lncRNA-based signature and immune responses in HCC. (A) Relative proportion of 22 different immune cells based on CIBERSORT in the low-risk group and the high-risk group. Immune cells in red indicated that there was a significant difference within the two groups. (B-I) The proportion of M0 macrophages, neutrophil, activated memory CD4+ T cells, follicular helper T cells, regulatory T cells, activated mast cell, monocyte and resting memory CD4+ T cells in the low-risk group and the high-risk group. (J) Heat map showing the relations between risk score and various immune checkpoints via Pearson test. (K) PDCD1 and CD274 were significantly upregulated in the high-risk group. lncRNAs, long noncoding RNAs; HCC, hepatocellular carcinoma. *p < 0.05, **p < 0.01, and ***p < 0.001.