Table 2.
Univariate analysis between SVD imaging markers and standardized cognitive measures.
| Variables | The presence of CMBs | The presence of lacunes | Total WMH | BG-EPVS | CSO-EPVS | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| r | p value | r | p value | r | p value | r | p value | r | p value | |
| MMSE | 0.10 | 0.201 | −0.05 | 0.503 | −0.09 | 0.259 | −0.06 | 0.491 | 0.02 | 0.773 |
| MoCA-BJ | 0.05 | 0.475 | −0.19 | 0.018 | −0.05 | 0.561 | −0.12 | 0.129 | 0.004 | 0.962 |
| C-RAVLT (IR) | −0.01 | 0.863 | −0.21 | 0.012 | −0.04 | 0.629 | −0.07 | 0.436 | 0.013 | 0.873 |
| C-RAVLT (DR) | 0.008 | 0.920 | −0.27 | 0.001 | −0.07 | 0.391 | −0.11 | 0.197 | −0.08 | 0.330 |
| Stroop-Atime,s | −0.04 | 0.586 | 0.04 | 0.654 | 0.34 | <0.001 | 0.04 | 0.607 | 0.11 | 0.215 |
| Stroop-Acorrect | −0.008 | 0.923 | −0.23 | 0.006 | −0.02 | 0.833 | −0.04 | 0.615 | −0.09 | 0.262 |
| Stroop-Btime,s | 0.06 | 0.512 | 0.06 | 0.469 | 0.27 | 0.001 | −0.07 | 0.431 | 0.15 | 0.071 |
| Stroop-Bcorrect | 0.06 | 0.467 | 0.03 | 0.731 | −0.04 | 0.585 | 0.06 | 0.503 | 0.07 | 0.414 |
| Stroop-Ctime,s | 0.09 | 0.239 | 0.12 | 0.150 | 0.25 | 0.002 | 0.02 | 0.819 | 0.14 | 0.102 |
| Stroop-Ccorrect | −0.06 | 0.496 | −0.10 | 0.217 | −0.16 | 0.059 | −0.02 | 0.799 | −0.11 | 0.198 |
| STT-A,s | −0.05 | 0.624 | 0.08 | 0.338 | 0.25 | 0.006 | 0.10 | 0.302 | 0.10 | 0.298 |
| STT-B,s | −0.09 | 0.297 | 0.08 | 0.419 | 0.24 | 0.010 | 0.02 | 0.806 | 0.03 | 0.785 |
SVD, cerebral small vessel disease; CMB, cerebral microbleeds; WMH, white matter hyperintensity; EPVS, enlarged perivascular spaces; BG: basal ganglia; CSO, centrum semiovale; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment-Beijing version; C-RAVLT (IR), The Chinese Rey Auditory Verbal Learning Test (immediate recall); C-RAVLT (DR), The Chinese Rey Auditory Verbal Learning Test (delayed recall); STT, Shape Trail Test. Bold values are statistically significant.