Figure 3.

Timeline for blood biomarker developments during the last decade (figure reproduced from from [34] by kind permission of the publishers under Creative Commons licence https://creativecommons.org/licenses/by/4.0/). Abbreviations: Simoa, single molecule array; Aβ42, the 42 amino acid form of amyloid β; T-tau, total-tau; IP-LC/MS, immunoprecipitation liquid chromatography-mass spectrometry; IP-MALDI, immunoprecipitation matrix-assisted laser desorption/ionization; Aβ40, the 40 amino acid form of amyloid β; NfL, neurofilament light; P-tau181, tau phosphorylated at amino acid 181; P-tau217, tau phosphorylated at amino acid 217; ECL, electrochemiluminescence [34].