TABLE 2.
18 key target information.
| Num | Target name | Gene name | UniProt ID | Degree |
|---|---|---|---|---|
| 1 | Signal transducer and activator of transcription 3 | STAT3 | P40763 | 50 |
| 2 | Heat shock protein HSP 90-alpha | HSP90AA1 | P07900 | 44 |
| 3 | Caspase-3 | CASP3 | P42574 | 36 |
| 4 | PI3-kinase subunit alpha | PIK3CA | P42336 | 35 |
| 5 | Hypoxia-inducible factor 1-alpha | HIF1A | Q16665 | 35 |
| 6 | Estrogen receptor alpha | ESR1 | P03372 | 34 |
| 7 | Bcl-2-like protein 1 | BCL2L1 | Q07817 | 33 |
| 8 | Matrix metalloproteinase-9 | MMP9 | P14780 | 32 |
| 9 | Toll-like receptor 4 | TLR4 | O00206 | 32 |
| 10 | Prostaglandin G/H synthase 2 | PTGS2 | P35354 | 30 |
| 11 | Mitogen-activated protein kinase 1 | MAPK1 | P28482 | 29 |
| 12 | PI3-kinase regulatory subunit alpha | PIK3R1 | P27986 | 28 |
| 13 | Tyrosine-protein kinase Lyn | LYN | P07948 | 27 |
| 14 | Inhibitor of nuclear factor kappa-B kinase subunit beta | IKBKB | O14920 | 26 |
| 15 | Nuclear factor NF-kappa-B p105 subunit | NFKB1 | P19838 | 26 |
| 16 | Induced myeloid leukemia cell differentiation protein Mcl-1 | MCL1 | Q07820 | 25 |
| 17 | C-X-C chemokine receptor type 4 | CXCR4 | P61073 | 25 |
| 18 | Caspase-8 | CASP8 | Q14790 | 25 |